The Effect of Chlorhexidine on Ventilatory Patient in ICU

Research Methodologies Identification


Elswick Jr., R. K., Grap, M. J., Munro, C. L., Hamilton, V. A., Sessler, C. N., and Ward, K. R. (2011). In trauma patients, a single early application of chlorhexidine lowers ventilator-associated pneumonia—the Journal of Acute and Critical Care, Heart & Lung, 40(5), e115-e122.


Motives for Selecting the Article


Because it addresses the problem—namely, the connection between ventilator-acquired pneumonia and the impact of chlorhexidine oral microbial flora—the study by Grap et al. (2011) was chosen.


Objectives of the Study


The study aimed to assess how early (within 12 hours of intubation) versus control (no swab) chlorhexidine treatment affected oral microbial flora and ventilator-acquired pneumonia.


Research Methods


Grap et al. (2011) acquired data using a quantitative research method. The sample for the researchers’ experimental investigation consisted of 135 trauma patients. Participants were randomly divided into treatment and control groups for the trial.


Strength of Research Methodology


The study’s experimental research design obtained high dependability and validity scores. The blinding throughout the assignment process and the random assignment of individuals to the treatment and control groups are two factors that contribute to the methodology’s success.





  1. Richards (2013). For patients receiving mechanical ventilation, oral hygiene routines based on chlorhexidine reduce the incidence of ventilator-associated pneumonia. Evid Based Dentistry, 91-2, 14 (3).


Motives for Selecting the Article


The article was chosen for the evidence-based investigation because it focused on the function of chlorhexidine in preventing ventilator-acquired pneumonia.


Objectives of the Study


The trial’s goal was to see if utilizing oral hygiene routines based on chlorhexidine may reduce ventilator-acquired pneumonia in mechanically ventilated patients.


Research Methods


Richards (2013) used randomized controlled trials (RCTs) to evaluate the efficacy of chlorhexidine-based oral hygiene regimens. The tests included people who were using mechanical ventilation.


Strength of Research Methodology


The method’s internal and external validity are promoted by randomization and randomized controlled trials for a particular participant group. The reliability of the questionnaire used to collect and record the data enhanced the reliability of the study.

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